SCHEMBL28429062

SCHEMBL28429062

Fc1cccc(-c2ncncn2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 4/20 0.49
IDO1 P14902 2/20 0.46
EGLN2 Q96KS0 1/20 0.45
TAAR1 Q96RJ0 2/20 0.44
ESR2 Q92731 1/20 0.44
MAP4K4 O95819 2/20 0.44
KMO O15229 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 2/20 0.43
CYP17A1 P05093 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
NOTUM Q6P988 1/20 0.42
PDGFRB P09619 1/20 0.41
PDGFRA P16234 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
TSHR P16473 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4761792 0.84 CLK4 (0.42) HPGDSCLK4
SCHEMBL4398415 0.83 CLK4 (0.52) HPGDSIDO1TAAR1ESR2MAP4K4
SCHEMBL18327587 0.78 CLK4 (0.52) CLK4
SCHEMBL27095783 0.78 TAAR1 (0.56) HPGDSIDO1TAAR1ESR2TP53
SCHEMBL16719539 0.78 HPGDS (0.47) HPGDSIDO1EGLN2TAAR1ESR2
SCHEMBL21081879 0.77 GP6 (0.48) KMONOTUMALDH1A1
SCHEMBL31722154 0.76 TAAR1 (0.55) HPGDSIDO1TAAR1MAP4K4TP53
SCHEMBL10091170 0.76 HPGDS (0.54) HPGDSIDO1PDGFRBPDGFRA
SCHEMBL30933626 0.76 MAP4K4 (0.50) HPGDSTAAR1MAP4K4KMOKDM4E
SCHEMBL13155157 0.76 MAP4K4 (0.50) HPGDSTAAR1MAP4K4KMOKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454226-B Method for synthesizing 2,4, 6-trisubstituted 1,3,5-triazine compound by aromatic aldehyde and ammonium iodide 沅江华龙催化科技有限公司 2021-08-06 CN disclosed
CN-111454226-A Method for synthesizing 2,4, 6-trisubstituted 1,3,5-triazine compound by aromatic aldehyde and ammonium iodide 沅江华龙催化科技有限公司 2020-07-28 CN disclosed