Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429512 | 1.00 | SIGMAR1 (0.54) | SIGMAR1AGTR2CA1CA2CA4 | |
| SCHEMBL3496353 | 1.00 | SIGMAR1 (0.54) | SIGMAR1AGTR2CA1CA2CA4 | |
| SCHEMBL14714339 | 0.89 | CA1 (0.65) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL3491620 | 0.89 | CA1 (0.65) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL15279940 | 0.89 | CA1 (0.65) | SIGMAR1CA1CA2CA4CA9 | |
| SCHEMBL3494525 | 0.88 | CA1 (0.63) | SIGMAR1AGTR2CA1CA2CA4 | |
| SCHEMBL3494491 | 0.88 | LTA4H (0.47) | SIGMAR1AGTR2CA1CA2CA4 | |
| SCHEMBL20528042 | 0.87 | SIGMAR1 (0.51) | SIGMAR1AGTR2CA1CA2CA4 | |
| SCHEMBL5081090 | 0.87 | SIGMAR1 (0.51) | SIGMAR1AGTR2CA1CA2CA4 | |
| SCHEMBL22122721 | 0.87 | CA1 (0.53) | SIGMAR1AGTR2CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285793-B | Fluorine-substituted bimolecular carbazole derivative, and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2022-04-22 | — | — | CN | disclosed |
| CN-111285793-A | Fluorine-substituted bimolecular carbazole derivative, and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2020-06-16 | — | — | CN | disclosed |