Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428038 | 1.00 | HIF1A (0.44) | HIF1AEPAS1LIPGGPR84MEN1 | |
| SCHEMBL7088782 | 1.00 | HIF1A (0.44) | HIF1AEPAS1LIPGGPR84MEN1 | |
| SCHEMBL28429499 | 0.91 | TYR (0.39) | HIF1AEPAS1LIPGGPR84TYR | |
| SCHEMBL2037935 | 0.89 | GPR84 (0.41) | HIF1AEPAS1LIPGGPR84MEN1 | |
| SCHEMBL2041102 | 0.89 | GPR84 (0.41) | HIF1AEPAS1LIPGGPR84MEN1 | |
| SCHEMBL28423423 | 0.82 | SRC (0.41) | GPR84MEN1TSHRKMT2ATDP1 | |
| SCHEMBL31003471 | 0.82 | CDK1 (0.51) | HIF1ALIPGTP53CYP3A4PTGS2 | |
| SCHEMBL29818830 | 0.82 | HIF1A (0.41) | HIF1AEPAS1LIPGGPR84MEN1 | |
| SCHEMBL8154554 | 0.82 | TYR (0.51) | LIPGMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL29818813 | 0.82 | TYR (0.44) | HIF1AEPAS1LIPGGPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293957-B | COFs film material with ultra-low dielectric constant | 北京理工大学 | 2020-10-20 | — | — | CN | claimed |
| CN-115582027-A | Preparation method of covalent organic framework organic solvent nanofiltration membrane modified by alkyl chains with different lengths | 天津工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-114058361-A | Preparation method of organogel with photochromism and fluorescence | 江南大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-111366627-B | Covalent organic framework porous structure of capillary tip and preparation method and application thereof | 南京大学 | 2021-02-26 | — | — | CN | disclosed |
| CN-111366627-A | Covalent organic framework porous structure of capillary tip and preparation method and application thereof | 南京大学 | 2020-07-03 | — | — | CN | disclosed |