Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037935 | 1.00 | GPR84 (0.41) | GPR84HIF1AEPAS1LIPGALOX5 | |
| SCHEMBL28429565 | 0.89 | HIF1A (0.44) | GPR84HIF1AEPAS1LIPGALOX5 | |
| SCHEMBL7088782 | 0.89 | HIF1A (0.44) | GPR84HIF1AEPAS1LIPGALOX5 | |
| SCHEMBL28428038 | 0.89 | HIF1A (0.44) | GPR84HIF1AEPAS1LIPGALOX5 | |
| SCHEMBL2050571 | 0.84 | ALOX5 (0.47) | GPR84LIPGALOX5MEN1TP53 | |
| SCHEMBL3842135 | 0.84 | ALOX5 (0.47) | GPR84LIPGALOX5MEN1TP53 | |
| SCHEMBL4225017 | 0.84 | ALOX5 (0.47) | GPR84LIPGALOX5MEN1TP53 | |
| SCHEMBL21508896 | 0.84 | ALOX5 (0.47) | GPR84LIPGALOX5MEN1TP53 | |
| SCHEMBL351893 | 0.84 | ALOX5 (0.47) | GPR84LIPGALOX5MEN1TP53 | |
| SCHEMBL1685341 | 0.84 | ALOX5 (0.47) | GPR84LIPGALOX5MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8525131-B2 | Phosphorescent organic compounds | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-09-03 | — | — | US | claimed |
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-04 | — | — | US | claimed |
| WO-2011066415-A2 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-06-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | PAICS, PPIP5K2, PPA1 | GPR84 4622/4885HIF1A 4079/4885EPAS1 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.