Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423295 | 0.70 | NPC1 (0.45) | HTTMEN1KMT2AMAPTALDH1A1 | |
| Methyl Alcohol SCHEMBL27770206 | 0.70 | HTT (0.68) | HTTTTRMEN1KMT2AMAPT | |
| SCHEMBL10962795 | 0.70 | HTT (0.55) | HTTTTRMEN1KMT2AMAPT | |
| SCHEMBL527567 | 0.70 | HTT (0.72) | HTTTTRMEN1KMT2AMAPT | |
| SCHEMBL29441283 | 0.70 | HTT (0.72) | HTTTTRMEN1KMT2AMAPT | |
| SCHEMBL14923429 | 0.69 | HTT (0.57) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30646027 | 0.68 | MEN1 (0.44) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29111047 | 0.68 | MEN1 (0.44) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28427729 | 0.68 | PDGFRA (0.44) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12004095 | 0.68 | HSPB1 (0.46) | HTTMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-A | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2020-06-09 | — | — | CN | disclosed |