Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29111047 | 1.00 | MEN1 (0.44) | MEN1KMT2ARXFP1HTTPDGFRA | |
| SCHEMBL28427729 | 0.74 | PDGFRA (0.44) | MEN1KMT2AHTTPDGFRAKDR | |
| SCHEMBL28426760 | 0.73 | SIGMAR1 (0.43) | MEN1KMT2ARXFP1HTTMAPT | |
| SCHEMBL12004509 | 0.71 | PDGFRA (0.57) | MEN1KMT2AHTTPDGFRAKDR | |
| SCHEMBL13915774 | 0.71 | HSPB1 (0.51) | MEN1KMT2AHTTPDGFRAKDR | |
| Methoxymethane SCHEMBL9362269 | 0.70 | HSPB1 (0.59) | MEN1KMT2AHTTMAPTALDH1A1 | |
| SCHEMBL27862972 | 0.70 | KMT2A (0.50) | MEN1KMT2ARXFP1HTTMAPT | |
| SCHEMBL23917581 | 0.70 | HSPB1 (0.50) | MEN1KMT2AHTTMAPTALDH1A1 | |
| P-Nitrophenol SCHEMBL28149477 | 0.69 | APP (0.60) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL114616 | 0.69 | HSPB1 (0.66) | MEN1KMT2AHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |