Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455395 | 0.85 | POLB (0.68) | HPGDALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL28284713 | 0.83 | PHGDH (0.61) | HPGDALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL7132525 | 0.83 | HPGD (1.00) | HPGDALDH1A1L3MBTL1CA12CA1 | |
| SCHEMBL27479149 | 0.83 | HPGD (1.00) | HPGDALDH1A1L3MBTL1CA12CA1 | |
| SCHEMBL367607 | 0.82 | HPGD (0.80) | HPGDALDH1A1L3MBTL1CA12CA1 | |
| SCHEMBL11857269 | 0.82 | HPGD (0.80) | HPGDALDH1A1L3MBTL1CA12CA1 | |
| Terephthalamide SCHEMBL13724808 | 0.82 | HPGD (0.80) | HPGDALDH1A1L3MBTL1CA12CA1 | |
| SCHEMBL367513 | 0.82 | HPGD (0.80) | HPGDALDH1A1L3MBTL1CA12CA1 | |
| Terephthalamide SCHEMBL1160108 | 0.82 | HPGD (0.80) | HPGDALDH1A1L3MBTL1CA12CA1 | |
| SCHEMBL4560822 | 0.82 | HPGD (0.80) | HPGDALDH1A1L3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423396-B | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-111423396-A | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2020-07-17 | — | — | CN | disclosed |