SCHEMBL28429896

SCHEMBL28429896

C=CC(=O)OOc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.61
HPGD P15428 4/20 0.61
CYP1A2 P05177 2/20 0.61
PGR P06401 2/20 0.61
SLC6A2 P23975 2/20 0.61
CYP2C19 P33261 2/20 0.61
MAPK1 P28482 2/20 0.61
HTT P42858 2/20 0.61
ALDH1A1 P00352 1/20 0.61
CYP2D6 P10635 1/20 0.61
PDE4A P27815 1/20 0.61
HRH1 P35367 1/20 0.61
SLC6A3 Q01959 1/20 0.61
PDE4D Q08499 1/20 0.61
MEN1 O00255 1/20 0.56
USP2 O75604 1/20 0.56
GAA P10253 1/20 0.56
KMT2A Q03164 1/20 0.56
KEAP1 Q14145 1/20 0.56
NFE2L2 Q16236 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989072 0.89 HPGD (0.64) LMNAHPGDCYP1A2PGRSLC6A2
SCHEMBL30173685 0.89 HPGD (0.64) LMNAHPGDCYP1A2PGRSLC6A2
SCHEMBL18049515 0.84 LMNA (0.52) LMNAHPGDCYP1A2PGRSLC6A2
1,1-Dichloroethene SCHEMBL9290894 0.84 HPGD (0.58) LMNAHPGDCYP1A2PGRSLC6A2
SCHEMBL27850227 0.83 HPGD (0.68) LMNAHPGDCYP1A2PGRSLC6A2
Alcohol SCHEMBL7640358 0.83 HPGD (0.60) LMNAHPGDCYP1A2PGRSLC6A2
SCHEMBL14845425 0.82 ELANE (0.50) LMNAHPGDALDH1A1MEN1GAA
SCHEMBL10765322 0.82 HPGD (0.56) LMNAHPGDCYP1A2PGRSLC6A2
SCHEMBL3118907 0.81 LMNA (0.66) LMNAHPGDCYP1A2PGRSLC6A2
SCHEMBL31425010 0.81 HPGD (0.62) LMNAHPGDCYP1A2PGRSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116670216-A Sulfide-containing stabilizer systems for thiol-ene and thiol-alkyne compositions 布卢洛伯克有限公司 2023-08-29 CN disclosed
CN-115350659-A Method for preparing capsules sensitive to pH or ultraviolet radiation and capsules obtained thereby 卡莉西亚公司 2022-11-18 CN disclosed
CN-111344057-B Method for preparing capsules sensitive to pH or ultraviolet radiation and capsules obtained thereby 卡莉西亚公司 2022-09-27 CN disclosed
CN-111344057-A Method for preparing capsules sensitive to pH or ultraviolet radiation and capsules obtained thereby 卡莉西亚公司 2020-06-26 CN disclosed