Ethylene Glycol

Ethylene Glycol

SCHEMBL28430213

CCCCCCCCCCCCSCCCC(c1ccc(O)c(C(C)(C)C)c1C)c1ccc(O)c(C(C)(C)C)c1C.OCCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.36
ESR2 Q92731 4/20 0.36
TP53 P04637 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33
TYR P14679 2/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
PLA2G4B P0C869 1/20 0.30
GMNN O75496 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
BLM P54132 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11132347 0.96 ESR1 (0.38) ESR1ESR2TP53CYP2C9CYP2D6
SCHEMBL6394389 0.79 CYP2D6 (0.37) TP53CYP2C9CYP2D6ALOX15CYP2C19
SCHEMBL30623136 0.78 TP53 (0.50) ESR1ESR2TP53CYP2C9CYP2D6
SCHEMBL1070452 0.78 TP53 (0.50) ESR1ESR2TP53CYP2C9CYP2D6
SCHEMBL7539719 0.77 TYR (0.31) ESR1ESR2TYR
SCHEMBL28428085 0.74 TYR (0.37) ESR1ESR2TP53CYP2C9CYP2D6
SCHEMBL2800660 0.71 TYR (0.47) TYR
SCHEMBL29404559 0.71 TYR (0.47) TYR
SCHEMBL11297701 0.68 ALOX15 (0.67) ESR1ESR2TP53CYP2C9CYP2D6
SCHEMBL4651373 0.66 RORC (0.35) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111433231-A Method for producing styrene resin and styrene resin molded body 出光兴产株式会社 2020-07-17 CN disclosed