Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 8/20 | 0.37 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407481 | 0.90 | EPHX2 (0.48) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL28168823 | 0.85 | LCK (0.45) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL28168423 | 0.83 | ELANE (0.50) | EPHX2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29669840 | 0.83 | EPHX2 (0.53) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL28783594 | 0.83 | EPHX2 (0.53) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL28872388 | 0.80 | RAB9A (0.61) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL30475405 | 0.80 | RAB9A (0.61) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL28437043 | 0.76 | EPHX2 (0.47) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL28437044 | 0.75 | EPHX2 (0.46) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL28168314 | 0.74 | LCK (0.47) | EPHX2MAPTLCKALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107129428-B | Anthraquinone compound and preparation method and application thereof | 云南中烟工业有限责任公司 | 2020-06-16 | — | — | CN | claimed |
| CN-107129428-B | Anthraquinone compound and preparation method and application thereof | 云南中烟工业有限责任公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-107129428-B | Anthraquinone compound and preparation method and application thereof | 云南中烟工业有限责任公司 | 2020-06-16 | — | — | CN | disclosed |