Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 2/20 | 0.36 |
| ▸ | POR | P16435 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168314 | 0.89 | LCK (0.47) | LCKELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28430344 | 0.85 | EPHX2 (0.46) | LCKELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28168423 | 0.80 | ELANE (0.50) | ELANENPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL30485987 | 0.74 | LCK (0.58) | LCKELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28407481 | 0.74 | EPHX2 (0.48) | LCKELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16226054 | 0.73 | EPHX2 (0.57) | LCKELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4729669 | 0.71 | LCK (0.58) | LCKELANENPC1RAB9AMAOA | |
| SCHEMBL27832512 | 0.71 | ELANE (0.55) | LCKELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28673474 | 0.71 | MEN1 (0.43) | ELANENPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL28872297 | 0.70 | EPHX2 (0.63) | LCKELANENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107129428-A | A kind of anthraquinone analog compound and its preparation method and application | 云南中烟工业有限责任公司 | 2017-09-05 | — | — | CN | disclosed |