2-Naphthaldehyde

2-Naphthaldehyde

SCHEMBL28430640

NNC(N)=O.O=Cc1ccc2ccccc2c1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HTT P42858 1/20 0.46
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
GRIN3A Q8TCU5 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
CYP3A4 P08684 1/20 0.44
RELA Q04206 1/20 0.43
RAB9A P51151 1/20 0.43
PTGS1 P23219 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Naphthaldehyde SCHEMBL6544637 0.83 RELA (0.55) KDM4EALDH1A1L3MBTL1CYP3A4RELA
2-Naphthaldehyde SCHEMBL27347080 0.83 RELA (0.58) KDM4EALDH1A1SMN1; SMN2GRIN2DGRIN3B
2-Naphthaldehyde SCHEMBL28110154 0.83 RELA (0.58) KDM4EALDH1A1SMN1; SMN2GRIN2DGRIN3B
2-Naphthaldehyde SCHEMBL30229844 0.83 RELA (0.58) KDM4EALDH1A1SMN1; SMN2GRIN2DGRIN3B
2-Naphthaldehyde SCHEMBL51340 0.83 RELA (0.58) KDM4EALDH1A1SMN1; SMN2GRIN2DGRIN3B
2-Naphthaldehyde SCHEMBL28251938 0.82 ALDH1A1 (0.50) LMNAKDM4EALDH1A1MEN1HPGD
2-Naphthaldehyde SCHEMBL28746939 0.81 KDM4E (0.53) KDM4EALDH1A1GRIN2DGRIN3BGRIN1
2-Naphthaldehyde SCHEMBL31458526 0.81 RELA (0.56) KDM4EALDH1A1SMN1; SMN2GRIN2DGRIN3B
2-Naphthaldehyde SCHEMBL3115512 0.81 RELA (0.56) KDM4EALDH1A1SMN1; SMN2GRIN2DGRIN3B
2-Naphthaldehyde SCHEMBL3118600 0.81 RELA (0.56) KDM4EALDH1A1SMN1; SMN2GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109884224-B Carbazochrome sodium sulfonate and method for measuring content of semicarbazide hydrochloride in preparation thereof 四川联成迅康医药股份有限公司 2020-06-16 CN disclosed