Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19242423 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14382185 | 0.81 | KDM4E (0.81) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27547137 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6950568 | 0.81 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10848639 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| 6-Deoxy Penciclovir SCHEMBL4207112 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7453112 | 0.78 | KDM4E (0.65) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7456549 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL30052297 | 0.76 | HDAC6 (0.54) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL452417 | 0.76 | HDAC6 (0.54) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107488176-B | Method for synthesizing famciclovir impurity C | 浙江医药股份有限公司新昌制药厂 | 2020-07-21 | — | — | CN | disclosed |