Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452417 | 1.00 | HDAC6 (0.54) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL28184787 | 0.81 | FGFR1 (0.45) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL8839496 | 0.79 | HDAC6 (0.50) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL8840058 | 0.78 | KDM4E (0.51) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL3151968 | 0.78 | KDM4E (0.55) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL14642669 | 0.77 | CDK1 (0.56) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL8840050 | 0.77 | HSD17B10 (0.55) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL28431107 | 0.76 | KDM4E (0.60) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL469371 | 0.76 | HDAC6 (0.49) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL4551666 | 0.76 | HDAC6 (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427044-A | Pyrrolopyrimidines as complement inhibitors | 拜奥克里斯特制药公司 | 2022-12-02 | — | — | CN | disclosed |