Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28895873 | 0.97 | RAB9A (0.57) | RAB9AMITFNPC1TSHRDRD2 | |
| SCHEMBL28434070 | 0.87 | HRH3 (0.56) | RAB9ANPC1TSHRDRD2HTR2A | |
| SCHEMBL28428365 | 0.85 | HRH3 (0.58) | RAB9ANPC1TSHRDRD2HTR2A | |
| SCHEMBL28428239 | 0.85 | RAB9A (0.57) | RAB9AMITFNPC1TSHRDRD2 | |
| SCHEMBL28428270 | 0.85 | RAB9A (0.57) | RAB9AMITFNPC1TSHRDRD2 | |
| SCHEMBL28425585 | 0.84 | ALDH1A1 (0.55) | RAB9ANPC1TSHRDRD2HTR2A | |
| SCHEMBL28430228 | 0.83 | RAB9A (0.55) | RAB9AMITFNPC1TSHRDRD2 | |
| SCHEMBL28438404 | 0.83 | HRH3 (0.61) | RAB9ANPC1TSHRHRH3ALDH1A1 | |
| SCHEMBL28896081 | 0.82 | RAB9A (0.56) | RAB9AMITFNPC1TSHRDRD2 | |
| SCHEMBL28436689 | 0.82 | HRH3 (0.63) | RAB9ANPC1TSHRHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320617-A | Phenyl oxadiazole derivative and preparation method and application thereof | 华中科技大学 | 2020-06-23 | — | — | CN | disclosed |