Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.45 |
| ▸ | RAB9A | P51151 | 11/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28426486 | 0.82 | MAPT (0.34) | KDM4EMAPTCHRNB2CHRNA5CHRNA4 | |
| SCHEMBL28428578 | 0.82 | CHRNB2 (0.38) | NPC1RAB9AMAPTALDH1A1CHRNB2 | |
| SCHEMBL28438715 | 0.82 | CHRNB2 (0.38) | NPC1CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL28428570 | 0.82 | NPC1 (0.50) | NPC1RAB9AKDM4EPKMRECQL | |
| SCHEMBL28428575 | 0.82 | KDM4E (0.42) | NPC1RAB9AKDM4EPKMNFKB1 | |
| SCHEMBL4407197 | 0.81 | ABCG2 (0.46) | NPC1RAB9AKDM4EPKMMAPT | |
| SCHEMBL28432163 | 0.81 | NPC1 (0.42) | NPC1RAB9AKDM4ERECQLMAPT | |
| SCHEMBL28436992 | 0.81 | HTT (0.47) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL28425959 | 0.81 | ALDH1A1 (0.41) | NPC1RAB9AKDM4EMAPTL3MBTL1 | |
| SCHEMBL28428686 | 0.80 | GRM5 (0.44) | MAPTL3MBTL1ALDH1A1CHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057023-A | 1-aryl-tetrazole-5-nitrile and 2-aryl-tetrazole-5-nitrile and preparation method thereof | 天津大学 | 2020-04-24 | — | — | CN | disclosed |