Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 7/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719782 | 0.94 | PTGDR2 (0.41) | PTGDR2BRAFAKR1C2AKR1C1FTO | |
| Trifluoroacetic Acid SCHEMBL28436261 | 0.90 | DHODH (0.34) | PTGDR2L3MBTL1PDE10AFFAR1NPC1 | |
| SCHEMBL28432284 | 0.85 | BRAF (0.36) | PTGDR2BRAF | |
| SCHEMBL16720180 | 0.84 | DHODH (0.37) | PTGDR2AKR1C2AKR1C1FFAR1NPC1 | |
| Trifluoroacetic Acid SCHEMBL28439757 | 0.83 | PDE10A (0.36) | L3MBTL1PDE10AFFAR1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL16720276 | 0.82 | NPC1 (0.43) | PTGS1PTGS2AKR1C2AKR1C1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28437063 | 0.82 | DHODH (0.37) | PTGDR2FFAR1HAO1 | |
| SCHEMBL18109265 | 0.80 | PTGDR2 (0.36) | PTGDR2BRAFAKR1C2AKR1C1NPC1 | |
| SCHEMBL16719381 | 0.79 | HAO1 (0.36) | PTGDR2HAO1 | |
| SCHEMBL16720455 | 0.77 | NPC1 (0.45) | PTGDR2L3MBTL1FTOFFAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934425-B | EBNA1 inhibitors and methods of use thereof | 威斯塔解剖学和生物学研究所 | 2020-08-07 | — | — | CN | disclosed |