Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720351 | 0.93 | NPC1 (0.38) | FFAR1NPC1RAB9AGRM5GAA | |
| Trifluoroacetic Acid SCHEMBL16720276 | 0.89 | NPC1 (0.43) | PDE10AFFAR1NPC1RAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL28437063 | 0.85 | DHODH (0.37) | FFAR1KMT2APOLBKDM4EDHODH | |
| SCHEMBL28439756 | 0.84 | CYP1A2 (0.33) | KCNH2GRM5 | |
| SCHEMBL16720455 | 0.83 | NPC1 (0.45) | FFAR1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL16720597 | 0.83 | NPC1 (0.49) | FFAR1NPC1RAB9AGAAKMT2A | |
| Trifluoroacetic Acid SCHEMBL28432286 | 0.83 | PTGDR2 (0.38) | PDE10AFFAR1NPC1RAB9AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28436261 | 0.83 | DHODH (0.34) | PDE10AFFAR1NPC1RAB9AGAA | |
| SCHEMBL16720829 | 0.81 | NPC1 (0.49) | FFAR1NPC1RAB9AKMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL28432317 | 0.81 | CCNC (0.38) | NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934425-B | EBNA1 inhibitors and methods of use thereof | 威斯塔解剖学和生物学研究所 | 2020-08-07 | — | — | CN | disclosed |