Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720767 | 0.94 | HAO1 (0.39) | DHODHHAO1HSD17B10SLC16A3FFAR1 | |
| SCHEMBL16719381 | 0.88 | HAO1 (0.36) | DHODHHAO1HSD17B10SLC16A3MEN1 | |
| SCHEMBL28437061 | 0.86 | KDM4E (0.34) | DHODHCSF1RMEN1KMT2ACDC7 | |
| Trifluoroacetic Acid SCHEMBL28439757 | 0.85 | PDE10A (0.36) | DHODHFFAR1KMT2AKDM4EPOLB | |
| Trifluoroacetic Acid SCHEMBL16720276 | 0.82 | NPC1 (0.43) | DHODHHAO1HSD17B10FFAR1KDM4E | |
| Trifluoroacetic Acid SCHEMBL28436261 | 0.82 | DHODH (0.34) | DHODHHAO1FFAR1PTPN7PTGDR2 | |
| Trifluoroacetic Acid SCHEMBL28432286 | 0.82 | PTGDR2 (0.38) | HAO1FFAR1PTGDR2 | |
| SCHEMBL16720112 | 0.78 | FFAR1 (0.43) | DHODHHAO1SLC16A3FFAR1RXRA | |
| SCHEMBL16720351 | 0.78 | NPC1 (0.38) | DHODHHAO1FFAR1KMT2APOLB | |
| SCHEMBL16720455 | 0.77 | NPC1 (0.45) | HAO1HSD17B10FFAR1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934425-B | EBNA1 inhibitors and methods of use thereof | 威斯塔解剖学和生物学研究所 | 2020-08-07 | — | — | CN | disclosed |