Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432814 | 0.85 | MMP13 (0.51) | MMP13ALDH1A1POLBHTTKMT2A | |
| SCHEMBL24371959 | 0.78 | KMT2A (0.59) | ALDH1A1HTTKMT2AKDM4EGAA | |
| SCHEMBL18507163 | 0.77 | CA1 (0.55) | ALDH1A1POLBCA12CA1CA2 | |
| SCHEMBL1162783 | 0.77 | CYP1A2 (0.57) | ALDH1A1HTTKMT2AKDM4EGAA | |
| SCHEMBL18063385 | 0.77 | ALDH1A1 (0.53) | MMP13ALDH1A1POLBCA12CA1 | |
| SCHEMBL22230833 | 0.75 | CA1 (0.53) | MMP13ALDH1A1POLBCA12CA1 | |
| SCHEMBL22230835 | 0.75 | CA1 (0.53) | MMP13ALDH1A1POLBCA12CA1 | |
| SCHEMBL14839516 | 0.74 | TDP1 (0.60) | ALDH1A1HTTKMT2AKDM4EGAA | |
| SCHEMBL30811394 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL3472313 | 0.73 | AOC3 (0.43) | MMP13CA12CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-111132974-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-05-08 | — | — | CN | disclosed |