Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28433305 | 1.00 | BCHE (0.49) | BCHEACHECTSKPPARGPPARA | |
| SCHEMBL28436451 | 0.90 | CTSK (0.48) | CTSKPPARGPPARAMAPTPOLB | |
| SCHEMBL28436448 | 0.90 | CTSK (0.48) | CTSKPPARGPPARAMAPTPOLB | |
| SCHEMBL1429859 | 0.90 | PPARA (0.54) | CTSKPPARGPPARAMAPTPOLB | |
| SCHEMBL7700752 | 0.89 | SYK (0.48) | CTSKPPARGPPARAMAPTSYK | |
| SCHEMBL7700750 | 0.89 | SYK (0.48) | CTSKPPARGPPARAMAPTSYK | |
| SCHEMBL28433106 | 0.87 | SIRT2 (0.48) | BCHEACHEMEN1KMT2ATLR2 | |
| SCHEMBL28433105 | 0.87 | SIRT2 (0.48) | BCHEACHEMEN1KMT2ATLR2 | |
| SCHEMBL2215841 | 0.84 | PPARA (0.63) | PPARGPPARAMAPTSYK | |
| SCHEMBL6766498 | 0.84 | PPARA (0.63) | PPARGPPARAMAPTSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484543-B | Lipopeptide TLR2 agonist and medicinal composition and application thereof | 复旦大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-111484543-A | Lipopeptide T L R2 agonist and medicinal composition and application thereof | 复旦大学 | 2020-08-04 | — | — | CN | disclosed |