Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436448 | 1.00 | CTSK (0.48) | CTSKSIRT2SIRT1PPARGPPARA | |
| SCHEMBL28433307 | 0.90 | BCHE (0.49) | CTSKPPARGPPARAMAPTPOLB | |
| SCHEMBL28433305 | 0.90 | BCHE (0.49) | CTSKPPARGPPARAMAPTPOLB | |
| SCHEMBL1429859 | 0.86 | PPARA (0.54) | CTSKPPARGPPARAMAPTPOLB | |
| SCHEMBL28439246 | 0.86 | SIRT2 (0.51) | SIRT2SIRT1SIRT3 | |
| SCHEMBL28439247 | 0.86 | SIRT2 (0.51) | SIRT2SIRT1SIRT3 | |
| SCHEMBL28433139 | 0.81 | PPARA (0.57) | CTSKPPARGPPARAMAPT | |
| SCHEMBL28433137 | 0.81 | PPARA (0.57) | CTSKPPARGPPARAMAPT | |
| SCHEMBL7700750 | 0.81 | SYK (0.48) | CTSKSIRT2SIRT1PPARGPPARA | |
| SCHEMBL7700752 | 0.81 | SYK (0.48) | CTSKSIRT2SIRT1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484543-B | Lipopeptide TLR2 agonist and medicinal composition and application thereof | 复旦大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-111484543-A | Lipopeptide T L R2 agonist and medicinal composition and application thereof | 复旦大学 | 2020-08-04 | — | — | CN | disclosed |