SCHEMBL28433832

SCHEMBL28433832

C[C@]12CC[C@H]3[C@@H](CCC4=CCCC[C@@]43C)[C@@H]1CC[C@@H]2CC(O)(O)O

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 19/20 0.67
SHBG P04278 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9782727 0.87 CYP19A1 (0.72) CYP19A1SHBG
SCHEMBL9782731 0.87 CYP19A1 (0.72) CYP19A1SHBG
SCHEMBL194995 0.86 CYP19A1 (0.70) CYP19A1
SCHEMBL141797 0.86 CYP19A1 (0.70) CYP19A1
SCHEMBL4298015 0.85 CYP19A1 (0.69) CYP19A1SHBG
SCHEMBL3706757 0.84 CYP19A1 (0.67) CYP19A1SHBG
SCHEMBL29688557 0.84 CYP19A1 (0.67) CYP19A1SHBG
SCHEMBL28278507 0.84 CYP19A1 (0.67) CYP19A1
Ethylene SCHEMBL28038914 0.84 CYP19A1 (0.67) CYP19A1
SCHEMBL7611386 0.83 CYP19A1 (0.69) CYP19A1SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111349677-A Biocatalysis preparation method of steroid C1, 2-position dehydrogenation drug intermediate 中国科学院天津工业生物技术研究所 2020-06-30 CN disclosed