SCHEMBL194995

SCHEMBL194995

CC[C@H]1CC[C@H]2[C@@H]3CCC4=CCCC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141797 1.00 CYP19A1 (0.70) CYP19A1
Ethylene SCHEMBL28038914 0.98 CYP19A1 (0.67) CYP19A1
SCHEMBL28278507 0.90 CYP19A1 (0.67) CYP19A1
SCHEMBL9782731 0.89 CYP19A1 (0.72) CYP19A1
SCHEMBL9782727 0.89 CYP19A1 (0.72) CYP19A1
SCHEMBL4298015 0.87 CYP19A1 (0.69) CYP19A1
SCHEMBL7611386 0.87 CYP19A1 (0.69) CYP19A1
SCHEMBL29688557 0.86 CYP19A1 (0.67) CYP19A1
SCHEMBL28433832 0.86 CYP19A1 (0.67) CYP19A1
SCHEMBL5171014 0.86 CYP19A1 (0.64) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119339933-A Age estimation method based on multidimensional data 中国科学院北京基因组研究所(国家生物信息中心) 2025-01-21 CN claimed
CN-119324053-A Model and index for evaluating aging delaying effect of estrogen replacement therapy and application of model and index 中国科学院北京基因组研究所(国家生物信息中心) 2025-01-17 CN claimed
CN-118858479-A Kit for simultaneously detecting 90 steroid hormones and metabolites thereof in urine sample, detection method and sample pretreatment method 中国疾病预防控制中心环境与健康相关产品安全所 2024-10-29 CN claimed
CN-117030904-B Method for measuring 144 steroid hormones in environmental sample by liquid chromatography-mass spectrometry 北京林业大学 2023-12-19 CN claimed
CN-117030904-A Method for measuring 144 steroid hormones in environmental sample by liquid chromatography-mass spectrometry 北京林业大学 2023-11-10 CN claimed
CN-116270460-A Self-emulsifying drug delivery system (SEDDS) for ophthalmic drug delivery 阿勒根公司 2023-06-23 CN claimed
CN-116143857-A Preparation method and application of 21-position-iodo-steroid compound 天津药业研究院股份有限公司 2023-05-23 CN claimed
CN-113583075-B Preparation method of medroxyprogesterone 浙江神洲药业有限公司 2022-05-20 CN claimed
CN-108239133-A The synthetic method of -17 α -ol -3,20- diketone drugs of -16 Alpha-Methyl of 4- pregnenes 成都千叶龙华石油工程技术咨询有限公司 2018-07-03 CN claimed
CN-107257680-A Self Emulsifying Drug Delivery System (SEDDS) for ophthalmic drug delivery 阿勒根公司 2017-10-17 CN claimed
CN-104072647-B One class halogen containing polymers preparation and its as the method for oxidation reaction catalyst catalysis oxidation alcohol to aldehyde ketone 华东理工大学 2017-06-16 CN claimed
EP-2012796-A2 THE USE OF A GLUCOCORTICOID RECEPTOR II ANTAGONIST TO TREAT DEPRESSION IN PATIENTS TAKING IL-2 Corcept Therapeutics, Inc. (US) 2009-01-14 EP claimed
WO-2007131041-A2 THE USE OF A GLUCOCORTICOID RECEPTOR II ANTAGONIST TO TREAT DEPRESSION IN PATIENTS TAKING IL-2 CORCEPT THERAPEUTICS, INC. (US) 2007-11-15 WO claimed
US-20030060425-A1 Immune modulation method using steroid compounds BIOVIE INC. 2003-03-27 US claimed
US-4323512-A Process for the preparation of steroidal 17α-arylcarboxylates SCHERING CORPORATION (US) 1982-04-06 US claimed
US-4221787-A Esteramide prodrugs of anti-inflammatory corticosteroids INTERX RESEARCH CORPORATION (US) 1980-09-09 US claimed
JP-61001698-A None JP disclosed
JP-54157553-A None JP disclosed
US-3980680-A Process for the preparation of 21-desoxy-17-acyloxy-4-pregnenes and of 21-iodo-21-desoxy-17-acyl oxy-4-pregnene intermediates useful therein SCHERING CORPORATION (US) 1976-09-14 US disclosed
US-3716638-A 6ALPHA-METHYL-19-NOR-PROGESTERONE AND A PROCESS OF ITS MANUFACTURE CIBA GEIGY CORP 1973-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030060425-A1 Immune modulation method using steroid compounds HSD3B1, NR5A1, HSD17B1 CYP19A1 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.