Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 11/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434453 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ALMNATLR2 | |
| SCHEMBL28430465 | 0.88 | ALDH1A1 (0.47) | TLR2HTT | |
| SCHEMBL28430468 | 0.88 | ALDH1A1 (0.47) | TLR2HTT | |
| SCHEMBL1429727 | 0.87 | SLC1A3 (0.56) | SMN1; SMN2LMNASLC1A3SLC1A1HTT | |
| SCHEMBL28433106 | 0.84 | SIRT2 (0.48) | SMN1; SMN2NPC1RAB9ALMNATLR2 | |
| SCHEMBL28433105 | 0.84 | SIRT2 (0.48) | SMN1; SMN2NPC1RAB9ALMNATLR2 | |
| SCHEMBL28433307 | 0.82 | BCHE (0.49) | TLR2ACHEMAPT | |
| SCHEMBL28433305 | 0.82 | BCHE (0.49) | TLR2ACHEMAPT | |
| SCHEMBL10825360 | 0.80 | SLC1A3 (0.62) | SMN1; SMN2LMNASLC1A3SLC1A1HTT | |
| SCHEMBL15372902 | 0.80 | SLC1A3 (0.62) | SMN1; SMN2LMNASLC1A3SLC1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484543-B | Lipopeptide TLR2 agonist and medicinal composition and application thereof | 复旦大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-111484543-A | Lipopeptide T L R2 agonist and medicinal composition and application thereof | 复旦大学 | 2020-08-04 | — | — | CN | disclosed |