SCHEMBL28435183

SCHEMBL28435183

CCOC(=O)C(C#N)CCCC#N

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.44
MEN1 O00255 3/20 0.44
TSHR P16473 3/20 0.37
ALDH1A1 P00352 3/20 0.36
GAA P10253 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTT P42858 2/20 0.34
LMNA P02545 2/20 0.34
CPB2 Q96IY4 1/20 0.33
POLB P06746 1/20 0.33
HSD17B10 Q99714 1/20 0.32
CASP1 P29466 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13916558 0.95 KMT2A (0.43) KMT2AMEN1TSHRALDH1A1GAA
SCHEMBL9562158 0.87 CA2 (0.40) KMT2AMEN1TSHRALDH1A1GAA
SCHEMBL1325862 0.85 ZDHHC7 (0.41) KMT2AMEN1TSHRALDH1A1GAA
SCHEMBL28288321 0.84 ZDHHC7 (0.43) LMNACPB2
SCHEMBL21646318 0.84 ZDHHC7 (0.43) LMNACPB2
SCHEMBL29374123 0.84 ZDHHC7 (0.43) LMNACPB2
SCHEMBL17079750 0.84 ZDHHC7 (0.43) LMNACPB2
SCHEMBL9183202 0.82 ALDH1A1 (0.39) KMT2AMEN1TSHRALDH1A1GAA
SCHEMBL28998281 0.82 CYP1A2 (0.47) KMT2ATSHRALDH1A1GAASMN1; SMN2
SCHEMBL28998284 0.82 AKR1B1 (0.36) KMT2AMEN1TSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517986-B Novel method for preparing aliphatic tri-nitrile and aliphatic tri-nitrile prepared by novel method 上海如鲲新材料股份有限公司 2023-09-26 CN disclosed
CN-111517986-A Novel method for preparing aliphatic trinitrile and aliphatic trinitrile prepared by using same 上海如鲲新材料有限公司 2020-08-11 CN disclosed