Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622821 | 0.79 | RAB9A (0.66) | RAB9ATSHRL3MBTL1HDAC3HDAC1 | |
| SCHEMBL28558081 | 0.77 | RAB9A (0.40) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL6089590 | 0.70 | NOTUM (0.58) | RAB9ATSHRL3MBTL1ALDH1A1NOTUM | |
| SCHEMBL6714690 | 0.68 | GAA (0.53) | RAB9ATSHRALDH1A1NPC1MEN1 | |
| SCHEMBL15515985 | 0.66 | NOTUM (0.34) | RAB9ATSHRL3MBTL1NOTUM | |
| SCHEMBL6230903 | 0.66 | NOTUM (0.38) | RAB9ATSHRL3MBTL1NOTUM | |
| SCHEMBL4620387 | 0.65 | ELANE (0.41) | RAB9ATSHRL3MBTL1NOTUM | |
| SCHEMBL4620599 | 0.64 | RAB9A (0.38) | RAB9ATSHRL3MBTL1HDAC8HDAC6 | |
| SCHEMBL16719757 | 0.64 | HDAC6 (0.41) | HDAC3HDAC1HDAC7HDAC2HDAC8 | |
| SCHEMBL1206513 | 0.63 | BUB1 (0.39) | L3MBTL1MEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032089-A | Compositions for treating stress-related disorders | 霍夫曼技术公司 | 2020-04-17 | — | — | CN | disclosed |