SCHEMBL28435633

SCHEMBL28435633

CS(=O)(=O)c1ccc(C(=O)O)c([N+](=O)[O-])c1.[NaH]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
LMNA P02545 3/20 0.53
ALDH3A1 P30838 3/20 0.49
MAPT P10636 3/20 0.47
GAA P10253 1/20 0.47
MEN1 O00255 2/20 0.45
RAB9A P51151 2/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 1/20 0.45
MITF O75030 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
CCR6 P51684 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TSHR P16473 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
SLC25A1 P53007 1/20 0.44
DTYMK P23919 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1202449 0.98 ALDH1A1 (0.56) ALDH1A1LMNAALDH3A1MAPTGAA
Hydrogen Peroxide SCHEMBL28991385 0.98 ALDH1A1 (0.56) ALDH1A1LMNAALDH3A1MAPTGAA
Hydrochloric Acid SCHEMBL9617579 0.97 ALDH1A1 (0.55) ALDH1A1LMNAALDH3A1MAPTGAA
SCHEMBL29035610 0.94 ALDH1A1 (0.52) ALDH1A1LMNAALDH3A1MAPTGAA
SCHEMBL29035621 0.92 ALDH1A1 (0.51) ALDH1A1LMNAALDH3A1MAPTGAA
Propylamine SCHEMBL18093556 0.89 ALDH1A1 (0.48) ALDH1A1LMNAALDH3A1MAPTGAA
SCHEMBL18093521 0.89 ALDH1A1 (0.48) ALDH1A1LMNAALDH3A1MAPTGAA
SCHEMBL18287474 0.85 ALDH3A1 (0.53) ALDH1A1LMNAALDH3A1MAPTGAA
SCHEMBL2084156 0.84 ALDH1A1 (0.51) ALDH1A1LMNAALDH3A1MAPTGAA
SCHEMBL366474 0.84 ALDH1A1 (0.51) ALDH1A1LMNAALDH3A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111302988-A Refining method of 2-nitro-4-methylsulfonyl benzoic acid 北京颖泰嘉和生物科技股份有限公司 2020-06-19 CN disclosed