SCHEMBL28435686

SCHEMBL28435686

CCCC(C(=O)O)(C(=O)Cl)C(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
FDPS P14324 2/20 0.34
ALDH1A1 P00352 5/20 0.33
TP53 P04637 2/20 0.33
TDP1 Q9NUW8 1/20 0.32
FFAR3 O14843 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL628235 0.87 TSHR (0.41) TSHRFDPSALDH1A1TP53TDP1
SCHEMBL28895340 0.86 ALDH1A1 (0.41) TSHRFDPSALDH1A1TP53TDP1
SCHEMBL375735 0.84 FFAR3 (0.38) TSHRFDPSALDH1A1TDP1FFAR3
Phosphine SCHEMBL5706624 0.81 FFAR3 (0.36) TSHRFDPSALDH1A1TDP1FFAR3
Hydrochloric Acid SCHEMBL3273722 0.81 FFAR3 (0.36) TSHRFDPSALDH1A1TDP1FFAR3
Phosphine SCHEMBL5706625 0.81 FFAR3 (0.36) TSHRFDPSALDH1A1TDP1FFAR3
SCHEMBL29208951 0.81 FFAR3 (0.36) TSHRFDPSALDH1A1TDP1FFAR3
Hydrochloric Acid SCHEMBL628236 0.81 FFAR3 (0.36) TSHRFDPSALDH1A1TDP1FFAR3
Hydrochloric Acid SCHEMBL28435687 0.81 FFAR3 (0.36) TSHRFDPSALDH1A1TDP1FFAR3
SCHEMBL27515063 0.81 FFAR3 (0.36) TSHRFDPSALDH1A1TDP1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113600029-A Antibacterial polyamide water treatment membrane with quaternary phosphonium salt and preparation method thereof 苏州普希环保科技有限公司 2021-11-05 CN disclosed
CN-113600030-A Quaternary phosphonium salt antibacterial polyamide separation membrane and preparation method thereof 苏州普希环保科技有限公司 2021-11-05 CN disclosed
CN-113600028-A Nano-silver antibacterial polyamide water treatment membrane and preparation method thereof 苏州普希环保科技有限公司 2021-11-05 CN disclosed
CN-112121646-A Antibacterial polyamide water treatment membrane with quaternary phosphonium salt and preparation method thereof 苏州普希环保科技有限公司 2020-12-25 CN disclosed
CN-112090292-A Quaternary phosphonium salt antibacterial polyamide separation membrane and preparation method thereof 苏州普希环保科技有限公司 2020-12-18 CN disclosed
CN-112090291-A Nano-silver antibacterial polyamide water treatment membrane and preparation method thereof 苏州普希环保科技有限公司 2020-12-18 CN disclosed
CN-111936427-A Sulfate ion removal system and method 日东电工株式会社 2020-11-13 CN disclosed
CN-110314558-B Separation membrane 日东电工株式会社 2020-09-29 CN disclosed
CN-109925890-B Separation membrane 日东电工株式会社 2020-06-19 CN disclosed