Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 known ✓ | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 known ✓ | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.36 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL628236 | 1.00 | FFAR3 (0.36) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Hydrochloric Acid SCHEMBL28435687 | 1.00 | FFAR3 (0.36) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL375735 | 0.97 | FFAR3 (0.38) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL27515063 | 0.94 | FFAR3 (0.36) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL28110688 | 0.94 | FFAR3 (0.36) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Phosphine SCHEMBL5706625 | 0.94 | FFAR3 (0.36) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Phosphine SCHEMBL5706624 | 0.94 | FFAR3 (0.36) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL29208951 | 0.94 | FFAR3 (0.36) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Hydrazine SCHEMBL27653931 | 0.92 | ALDH1A1 (0.38) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Phosphoric Acid SCHEMBL2368341 | 0.87 | FDPS (0.46) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119565382-A | Method for cleaning reverse osmosis membrane and reverse osmosis membrane prepared by same | 万华化学集团股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-115845615-B | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-112827368-B | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-113600040-B | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-114053876-B | Preparation method of anti-pollution reverse osmosis membrane | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-115845615-A | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-114053876-A | Preparation method of anti-pollution reverse osmosis membrane | 万华化学集团股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-113600040-A | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-110354682-A | A kind of stable against biological contamination reverse osmosis membrane and its preparation method and application | 万华化学集团股份有限公司 | 2019-10-22 | — | — | CN | claimed |
| EP-1020218-B1 | COMPOSITE REVERSE OSMOSIS MEMBRANE AND PROCESS FOR PREPARING THE SAME | NITTO DENKO CORP (JP) | 2003-05-21 | — | — | EP | claimed |
| EP-1020218-A1 | COMPOSITE REVERSE OSMOSIS MEMBRANE AND PROCESS FOR PREPARING THE SAME | NITTO DENKO CORPORATION (JP) | 2000-07-19 | — | — | EP | claimed |
| CN-120076861-A | Composite semipermeable membrane and spiral membrane element | 日东电工株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-119565382-A | Method for cleaning reverse osmosis membrane and reverse osmosis membrane prepared by same | 万华化学集团股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-115845615-B | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-114146567-B | Preparation process of epoxy modified reverse osmosis membrane, reverse osmosis membrane and application of reverse osmosis membrane | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-0787525-A1 | Highly permeable composite reverse osmosis membrane | NITTO DENKO CORPORATION (JP) | 1997-08-06 | — | — | EP | disclosed |
| US-5614099-A | POLYAMIDE SKIN LAYER COATED WITH CROSSLINKED POLYETHYLENIMINE, ANIONIC AND CATIONIC POLYMERS, MULTISTAGE DESALINATION | NITTO DENKO CORPORATION (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0752266-A2 | Highly permeable composite reverse osmosis membrane | NITTO DENKO CORPORATION (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-5576057-A | COATING A POROUS SUBSTRATE WITH A COMPOUND HAVING AT LEAST TWO REACTIVE AMINO GROUPS THEN COATING WITH A SOLUTION CONTAINING A POLYFUNCTIONAL ACID HALIDE | NITTO DENKO CORPORATION (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0718029-A2 | Method for producing highly permeable composite reverse osmosis membrane | NITTO DENKO CORPORATION (JP) | 1996-06-26 | — | — | EP | disclosed |