Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28435693

COC(=O)c1ncn2c1CN[C@@H](C)C2.O=C(O)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
HCRTR2 O43614 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22053570 0.92 NPSR1 (0.34) HCRTR2
SCHEMBL21958277 0.84
Trifluoroacetic Acid SCHEMBL29457296 0.79 DRD3 (0.39) KDM4E
SCHEMBL22017328 0.76 GSK3B (0.39)
SCHEMBL22017323 0.70
SCHEMBL3091366 0.70 CHRM3 (0.40) KDM4E
SCHEMBL20691683 0.68 DRD3 (0.44) KDM4E
SCHEMBL18366333 0.66 APOBEC3A (0.39) KDM4E
SCHEMBL31700199 0.65 NPSR1 (0.33) KDM4E
Trifluoroacetic Acid SCHEMBL29817382 0.64 RAB9A (0.53) KDM4EHCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109952305-B Piperazino heteroaryl derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2022-06-21 CN disclosed
CN-111484497-B Pharmaceutical salt and crystal form of imidazo [1,5-a ] pyrazine derivative and preparation method thereof 江苏恒瑞医药股份有限公司 2021-07-02 CN disclosed
CN-111484498-B Crystal form of imidazo [1,5-a ] pyrazine compound and preparation method thereof 江苏恒瑞医药股份有限公司 2021-05-14 CN disclosed
CN-111484497-A Pharmaceutical salt and crystal form of imidazo [1,5-a ] pyrazine derivative and preparation method thereof 江苏恒瑞医药股份有限公司 2020-08-04 CN disclosed
CN-111484498-A Crystal form of imidazo [1,5-a ] pyrazine compound and preparation method thereof 江苏恒瑞医药股份有限公司 2020-08-04 CN disclosed