Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL21144490 | 0.83 | KMT2A (0.38) | NFE2L2POLBLMNAMAPTMEN1 | |
| SCHEMBL29629095 | 0.81 | NFE2L2 (0.40) | NFE2L2TRPA1PPARGPOLBNPC1 | |
| SCHEMBL2843586 | 0.81 | NFE2L2 (0.40) | NFE2L2TRPA1PPARGPOLBNPC1 | |
| Ether SCHEMBL1170797 | 0.79 | NFE2L2 (0.43) | NFE2L2TRPA1PPARGLMNACTDSP1 | |
| Ether SCHEMBL4785780 | 0.75 | ALDH1A1 (0.40) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| Ether SCHEMBL2872980 | 0.74 | ALDH1A1 (0.39) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18141022 | 0.73 | KMT2A (0.40) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9420064 | 0.73 | NFE2L2 (0.49) | NFE2L2TRPA1PPARGLMNAMAPT | |
| SCHEMBL28245082 | 0.72 | KMT2A (0.39) | POLBMAPTMEN1KMT2AALDH1A1 | |
| Ether SCHEMBL563787 | 0.72 | NFE2L2 (0.50) | NFE2L2TRPA1PPARGPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130640-A1 | SEALANT COMPOSITION FOR REPAIRING A PUNCTURED TIRE | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2010-05-27 | — | — | US | disclosed |