Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | PGR | P06401 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | IL6 | P05231 | 1/20 | 0.53 |
| ▸ | GLUL | P15104 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL28140488 | 0.97 | HIF1A (0.59) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| Propionic Acid SCHEMBL27929927 | 0.95 | HIF1A (0.59) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| SCHEMBL141828 | 0.95 | HIF1A (0.62) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| Acetic Acid SCHEMBL27804797 | 0.95 | HIF1A (0.60) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| SCHEMBL141360 | 0.95 | HIF1A (0.61) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| Water SCHEMBL27961624 | 0.95 | HIF1A (0.61) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| Butyric Acid SCHEMBL27495006 | 0.93 | HIF1A (0.58) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| SCHEMBL5084683 | 0.93 | HIF1A (0.62) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| SCHEMBL1301994 | 0.93 | HIF1A (0.62) | HIF1ANR3C2NR3C1HSD17B10PGR | |
| SCHEMBL3488313 | 0.93 | HIF1A (0.63) | HIF1ANR3C2NR3C1HSD17B10PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111529684-A | Use of oral sustained release compositions containing cyclosporin | 卓越治疗有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-113661169-A | Phosphoramidate triphosphate salts of nucleotides as anticancer compounds | 努卡那有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-112119077-A | Kinase inhibitors | 曼彻斯特大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-111655681-A | Heterocyclylamino-substituted triazoles as modulators of Rho-associated protein kinase | 莱德克斯制药公共有限公司 | 2020-09-11 | — | — | CN | disclosed |