SCHEMBL1301994

SCHEMBL1301994

C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC(OC(=O)CCC(=O)O)[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 13/20 0.62
▸ SMN1; SMN2 Q16637 3/20 0.62
▸ HSD17B10 Q99714 4/20 0.61
▸ NR3C1 P04150 4/20 0.61
▸ PGR P06401 4/20 0.61
▸ NR3C2 P08235 4/20 0.61
▸ CYP2C19 P33261 3/20 0.61
▸ SERPINA6 P08185 3/20 0.61
▸ CYP3A4 P08684 3/20 0.61
▸ KMT2A Q03164 3/20 0.61
▸ NFKB1 P19838 2/20 0.61
▸ MAPT P10636 2/20 0.61
▸ SHBG P04278 1/20 0.61
▸ AR P10275 2/20 0.56
▸ ABCB11 O95342 1/20 0.56
▸ TNF P01375 1/20 0.56
▸ IL6 P05231 1/20 0.56
▸ GLUL P15104 1/20 0.56
▸ ADAM17 P78536 1/20 0.56
▸ GPBAR1 Q8TDU6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27571456 0.99 HIF1A (0.61) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
SCHEMBL27941428 0.99 HIF1A (0.61) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
SCHEMBL23456330 0.98 HIF1A (0.59) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
SCHEMBL6001323 0.97 HIF1A (0.65) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
SCHEMBL14931695 0.96 HIF1A (0.64) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
SCHEMBL249836 0.96 HIF1A (0.64) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
Butyric Acid SCHEMBL28140488 0.95 HIF1A (0.59) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
SCHEMBL1535104 0.94 HIF1A (0.63) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
Valeric Acid SCHEMBL28435896 0.93 HIF1A (0.57) HIF1ASMN1; SMN2HSD17B10NR3C1PGR
Propionic Acid SCHEMBL27929927 0.93 HIF1A (0.59) HIF1ASMN1; SMN2HSD17B10NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240408110-A1 PHARMACEUTICAL HYDROCORTISONE SOLUTION FOR INJECTION DEVICE CROSSJECT (FR) 2024-12-12 — — US claimed
EP-4429634-A1 PHARMACEUTICAL SOLUTION OF HYDROCORTISONE FOR INJECTION DEVICE Crossject (FR) 2024-09-18 — — EP claimed
CN-118251209-A Hydrocortisone pharmaceutical solution for injection device 克鲁斯杰克特公司 2024-06-25 — — CN claimed
WO-2023083825-A1 PHARMACEUTICAL SOLUTION OF HYDROCORTISONE FOR INJECTION DEVICE CROSSJECT (FR) 2023-05-19 — — WO claimed
EP-3532033-B1 PHARMACEUTICAL HYDROCORTISONE SOLUTION FOR AN INJECTION DEVICE CROSSJECT (FR) 2020-08-05 — — EP claimed
US-10456355-B1 Pharmaceutical hydrocortisone solution for an injection device CROSSJECT (FR) 2019-10-29 — — US claimed
US-20190314273-A1 PHARMACEUTICAL HYDROCORTISONE SOLUTION FOR AN INJECTION DEVICE CROSSJECT (FR) 2019-10-17 — — US claimed
EP-3829591-B1 HYDROCORTISONE FOR THE TREATMENT OF MASTITIS IN NON-HUMAN MAMMALS VIRBAC (FR) 2026-05-27 — — EP disclosed
US-20260091042-A1 AQUEOUS PHARMACEUTICAL FORMULATION OF HYDROCORTISONE SODIUM PHOSPHATE AND MONOTHIOGLYCEROL ANTARES PHARMA, INC. (US) 2026-04-02 — — US disclosed
US-12521404-B2 Aqueous pharmaceutical formulation of hydrocortisone sodium phosphate and monothioglycerol ANTARES PHARMA, INC. (US) 2026-01-13 — — US disclosed
US-12478629-B2 Use of glucocorticoids for the treatment of epithelial microbial infections of a fluid containing organ with a natural exterior orifice in mammals VIRBAC (FR) 2025-11-25 — — US disclosed
WO-2025136950-A1 MIXING AND DELIVERY SYSTEMS AND NEEDLE HUBS FOR SAME SOLUtion Medical, Inc. (US) 2025-06-26 — — WO disclosed
EP-4496575-A1 AQUEOUS PHARMACEUTICAL FORMULATION OF HYDROCORTISONE SODIUM PHOSPHATE AND MONOTHIOGLYCEROL Antares Pharma, Inc. (US) 2025-01-29 — — EP disclosed
US-9693956-B2 Liquid compositions capable of foaming and including active agents, and methods for making or developing same MIKA PHARMA GMBH 2017-07-04 — — US disclosed
US-20160022579-A1 Liquid Compositions Capable of Foaming and Including Active Agents, and Methods for Making or Developing Same MIKA PHARMA GMBH 2016-01-28 — — US disclosed
US-9005626-B2 Liquid compositions capable of foaming and including active agents, and methods for making or developing same MIKA PHARMA GMBH (DE) 2015-04-14 — — US disclosed
US-20110269704-A1 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FUR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2011-11-03 — — US disclosed
US-20110059117-A1 Liquid Compositions Capable of Foaming and Including Active Agents, and Methods for Making or Developing Same MIKA PHARMA GMBH (DE) 2011-03-10 — — US disclosed
US-20080255125-A1 Topically Applied Medicament for Animals BAYER HEALTHCARE AG (DE) 2008-10-16 — — US disclosed
CN-1759043-A Safety containers for biologically active substances and method for producing said container BAXTER HEALTHCARE SA (CH) 2006-04-12 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091042-A1 AQUEOUS PHARMACEUTICAL FORMULATION OF HYDROCORTISONE SODIUM PHOSPHATE AND MONOTHIOGLYCEROL NR3C1, HSD11B2, NR3C2 HIF1A 1532/4885SMN1; SMN2 4758/4885HSD17B10 835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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