SCHEMBL28435975

SCHEMBL28435975

NCCc1cccc2c1[nH]c1ccccc12.Nc1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
MAPK1 P28482 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
KIF11 P52732 4/20 0.47
CYP3A4 P08684 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
KEAP1 Q14145 1/20 0.47
HSD17B10 Q99714 1/20 0.47
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MPO P05164 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2A6 P11509 1/20 0.42
NFKB1 P19838 1/20 0.42
HTR1D P28221 1/20 0.42
HTR1B P28222 1/20 0.42
HTR2A P28223 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195190 0.88 MAPT (0.67) MAPTMAPK1NPSR1KIF11CYP3A4
SCHEMBL30131116 0.88 MAPT (0.67) MAPTMAPK1NPSR1KIF11CYP3A4
SCHEMBL14689281 0.79 MAPT (0.55) MAPTMAPK1NPSR1KIF11CYP3A4
SCHEMBL30357992 0.79 MAPT (0.55) MAPTMAPK1NPSR1KIF11CYP3A4
Hydrochloric Acid SCHEMBL8935716 0.78 MAPT (0.54) MAPTMAPK1NPSR1KIF11CYP3A4
SCHEMBL8026803 0.77 MAPT (0.52) MAPTMAPK1NPSR1KIF11CYP3A4
SCHEMBL11043168 0.76 TDP1 (0.50) MAPTMAPK1NPSR1KIF11CYP3A4
SCHEMBL11577428 0.75 KIF11 (0.53) MAPTMAPK1NPSR1KIF11CYP3A4
SCHEMBL21808458 0.75 KIF11 (0.53) MAPTMAPK1NPSR1KIF11CYP3A4
SCHEMBL29291020 0.74 KIF11 (0.52) MAPTMAPK1NPSR1KIF11CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111494227-A Hair strengthening composition and method for strengthening hair 知识产权全资有限公司 2020-08-07 CN disclosed
CN-110101590-A For handling the method and its kit of hair 知识产权全资有限公司 2019-08-09 CN disclosed
CN-105267066-B Method for treating hair and kit therefor 知识产权全资有限公司 2019-06-11 CN disclosed
CN-106265109-A Hair strengthening composition and method for strengthening hair and imparting excellent feel to hair 知识产权全资有限公司 2017-01-04 CN disclosed
CN-105902404-A Hair strengthening composition and method for strengthening hair 知识产权全资有限公司 2016-08-31 CN disclosed
CN-105902403-A Hair strengthening composition and method for strengthening hair 知识产权全资有限公司 2016-08-31 CN disclosed
CN-105496804-A Formula for treating hair and treating head psoriasis, kit and application thereof INTELLECTUAL PROPERTY WHOLLY-OWNED CO LTD 2016-04-20 CN disclosed
CN-105267066-A Method for treating hair and kit therefor INTELLECTUAL PROPERTY WHOLLY OWNED CO LTD 2016-01-27 CN disclosed