Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | ECE1 | P42892 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28441360 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL17685861 | 0.94 | KYNU (0.48) | ITGB3ITGA2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17685911 | 0.94 | KYNU (0.48) | ITGB3ITGA2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17685862 | 0.94 | KYNU (0.48) | ITGB3ITGA2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17685910 | 0.94 | KYNU (0.48) | ITGB3ITGA2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17695789 | 0.87 | MEN1 (0.46) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL17695787 | 0.87 | MEN1 (0.46) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL19986477 | 0.85 | KYNU (0.48) | ITGB3ITGA2BMEN1KMT2ACTSK | |
| SCHEMBL17693642 | 0.85 | KYNU (0.48) | ITGB3ITGA2BMEN1KMT2ACTSK | |
| SCHEMBL17693636 | 0.85 | KYNU (0.48) | ITGB3ITGA2BMEN1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111494395-B | Carbidopa and levodopa prodrugs and their use for treating parkinson's disease | 艾伯维公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-111454290-B | Carbidopa and levodopa prodrugs and their use for treating parkinson's disease | 艾伯维公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-111362980-B | Carbidopa and levodopa prodrugs and their use for treating parkinson's disease | 艾伯维公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-111494395-A | Carbidopa and levodopa prodrugs and their use for treating parkinson's disease | 艾伯维公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111454290-A | Carbidopa and levodopa prodrugs and their use for treating parkinson's disease | 艾伯维公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-111362980-A | Carbidopa and levodopa prodrugs and their use for treating parkinson's disease | 艾伯维公司 | 2020-07-03 | — | — | CN | disclosed |