SCHEMBL2843709

SCHEMBL2843709

CCCC(C(N)=O)=C(CC(C)C)CC(C)C

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CA2 P00918 1/20 0.33
CTSD P07339 1/20 0.32
FFAR3 O14843 3/20 0.32
HDAC3 O15379 3/20 0.32
HDAC1 Q13547 3/20 0.32
HDAC2 Q92769 3/20 0.32
HDAC8 Q9BY41 3/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28279159 0.78 ALDH1A1 (0.40) ALDH1A1CES2CES1CTSDFFAR3
Ammonia Solution, Strong SCHEMBL27555258 0.78 CES2 (0.39) ALDH1A1CES2CES1CTSDFFAR3
SCHEMBL28284837 0.77 CES2 (0.47) ALDH1A1TDP1CES2CES1CTSD
SCHEMBL3357465 0.73 ALDH1A1 (0.40) ALDH1A1TDP1CES2CES1CTSD
SCHEMBL11146830 0.71 FNTA (0.39) ALDH1A1TDP1CES2CES1CA2
SCHEMBL3361436 0.70 CES1 (0.41) ALDH1A1TDP1CES2CES1CTSD
SCHEMBL1720979 0.70 CES1 (0.41) ALDH1A1TDP1CES2CES1CTSD
Ammonia Solution, Strong SCHEMBL27608600 0.69 CES2 (0.46) ALDH1A1TDP1CES2CES1TSHR
SCHEMBL6636615 0.69 CES1 (0.39) ALDH1A1TDP1CES2CES1CTSD
SCHEMBL27671936 0.69 CES1 (0.39) ALDH1A1TDP1CES2CES1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010121042-A1 PROCESS FOR ABSORBING AND ADSORBING OIL DEGRADATION PRODUCTS FROM LUBRICATING OILS FLUITEC INTERNATIONAL (US) 2010-10-21 WO disclosed