Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28440007 | 0.81 | DGAT1 (0.40) | ARDGAT1PARP1ALOX5APFEN1 | |
| SCHEMBL29996842 | 0.80 | DGAT1 (0.44) | DGAT1HDAC1HDAC6ALOX5APFEN1 | |
| SCHEMBL28437548 | 0.80 | AR (0.46) | ARDGAT1PARP1HDAC1HDAC6 | |
| SCHEMBL27621512 | 0.76 | BTK (0.50) | PARP1PDK2ALDH1A1HSD17B10 | |
| SCHEMBL811354 | 0.74 | DGAT1 (0.62) | DGAT1PARP1HDAC1HDAC6LCK | |
| SCHEMBL3078849 | 0.74 | PARP1 (0.50) | ARPARP1HDAC1HDAC6LCK | |
| SCHEMBL1627106 | 0.74 | HDAC1 (0.63) | PARP1HDAC1HDAC6LCKKDM4E | |
| SCHEMBL28013892 | 0.72 | BTK (0.43) | PARP1PDK2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28439877 | 0.72 | PDK2 (0.39) | ARHDAC1HDAC6PDK2KDM4E | |
| SCHEMBL1512044 | 0.72 | ALDH1A1 (0.50) | PARP1LCKKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864426-B | Ultralow-expansion fluorine-containing polyimide film and preparation method and application thereof | 中国科学院化学研究所 | 2020-07-31 | — | — | CN | claimed |
| CN-115216004-A | Polyimide resin, polyimide film, flexible device, and electronic apparatus | 华为技术有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-108864426-B | Ultralow-expansion fluorine-containing polyimide film and preparation method and application thereof | 中国科学院化学研究所 | 2020-07-31 | — | — | CN | disclosed |