Mannitol

Mannitol

SCHEMBL28437582

O=C(O)CS.OCC(O)C(O)C(O)C(O)CO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.58
LMNA P02545 3/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TDP1 Q9NUW8 1/20 0.55
USP2 O75604 1/20 0.54
SLCO1B1 Q9Y6L6 1/20 0.54
KDM4E B2RXH2 2/20 0.41
OR51E2 Q9H255 1/20 0.38
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adonitol SCHEMBL28440151 0.95 PDE4A (0.52) PDE4ALMNAL3MBTL1TDP1USP2
E968 SCHEMBL28445480 0.89 PDE4A (0.44) PDE4ALMNAL3MBTL1TDP1USP2
E968 SCHEMBL9858617 0.89 PDE4A (0.44) PDE4ALMNAL3MBTL1TDP1USP2
E968 SCHEMBL10703757 0.89 PDE4A (0.44) PDE4ALMNAL3MBTL1TDP1USP2
Demannose SCHEMBL28441201 0.85 PDE4A (0.45) PDE4ALMNAL3MBTL1TDP1USP2
Mannitol SCHEMBL20481115 0.83 LMNA (0.65) PDE4ALMNAL3MBTL1TDP1USP2
Sorbitol SCHEMBL31013480 0.83 LMNA (0.73) PDE4ALMNAL3MBTL1TDP1USP2
Mannitol SCHEMBL30410531 0.83 LMNA (0.73) PDE4ALMNAL3MBTL1TDP1USP2
Mannitol SCHEMBL27844169 0.83 LMNA (0.73) PDE4ALMNAL3MBTL1TDP1USP2
Mannitol SCHEMBL19927163 0.81 LMNA (0.61) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106631779-B Polyol esters and their use in processing halogenated vinyl polymers 济南金昌树新材料科技有限公司 2020-07-14 CN disclosed