Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E968 SCHEMBL28445480 | 1.00 | PDE4A (0.44) | PDE4AOR51E2LMNAUSP2SLCO1B1 | |
| E968 SCHEMBL10703757 | 1.00 | PDE4A (0.44) | PDE4AOR51E2LMNAUSP2SLCO1B1 | |
| Mannitol SCHEMBL28437582 | 0.89 | PDE4A (0.58) | PDE4AOR51E2LMNAUSP2SLCO1B1 | |
| Adonitol SCHEMBL28440151 | 0.89 | PDE4A (0.52) | PDE4AOR51E2LMNAUSP2SLCO1B1 | |
| E968 SCHEMBL23467010 | 0.88 | PDE4A (0.37) | PDE4AOR51E2LMNAUSP2SLCO1B1 | |
| Thioglycolic Acid SCHEMBL27947118 | 0.85 | OR51E2 (0.43) | PDE4AOR51E2LMNAUSP2SLCO1B1 | |
| Dithioerythriol SCHEMBL9109286 | 0.83 | PDE4A (0.37) | PDE4AOR51E2LMNAUSP2SLCO1B1 | |
| Dithioerythriol SCHEMBL7523387 | 0.83 | PDE4A (0.37) | PDE4AOR51E2LMNAUSP2SLCO1B1 | |
| Glycerin SCHEMBL97353 | 0.82 | LMNA (0.53) | PDE4AOR51E2LMNASLC22A6SMN1; SMN2 | |
| Glycerin SCHEMBL560044 | 0.82 | LMNA (0.53) | PDE4AOR51E2LMNASLC22A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422836-A2 | Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-04-17 | — | — | EP | disclosed |