Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28443347 | 0.88 | GAA (0.48) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL6137213 | 0.83 | ALDH1A1 (0.54) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL28435242 | 0.79 | MAPT (0.52) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| Diethylamine SCHEMBL8883749 | 0.79 | GAA (0.52) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL30209788 | 0.77 | KDM4E (0.61) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL6949718 | 0.77 | GAA (0.56) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL31231118 | 0.77 | GAA (0.56) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL30686655 | 0.77 | GAA (0.56) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL6956135 | 0.76 | SMN1; SMN2 (0.62) | GAAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL11017680 | 0.76 | HTT (0.76) | GAAALDH1A1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518024-A | Preparation method of two high-purity felodipine impurities | 山东省药学科学院 | 2020-08-11 | — | — | CN | disclosed |