Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 20/20 | 1.00 |
| ▸ | SETDB1 | Q15047 | 2/20 | 0.63 |
| ▸ | BPTF | Q12830 | 1/20 | 0.55 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438090 | 1.00 | KAT2B (1.00) | KAT2BSETDB1BPTFKAT2A | |
| SCHEMBL29413001 | 0.78 | KAT2B (1.00) | KAT2BSETDB1BPTFKAT2A | |
| SCHEMBL31091734 | 0.74 | KAT2B (0.81) | KAT2BSETDB1BPTFKAT2A | |
| SCHEMBL29412997 | 0.72 | KAT2B (1.00) | KAT2BSETDB1BPTFKAT2A | |
| SCHEMBL31091717 | 0.70 | KAT2B (0.73) | KAT2BSETDB1BPTFKAT2A | |
| SCHEMBL29413023 | 0.67 | KAT2B (0.49) | KAT2BSETDB1 | |
| SCHEMBL17571635 | 0.67 | KAT2B (1.00) | KAT2BBPTF | |
| SCHEMBL30374596 | 0.67 | KAT2B (0.50) | KAT2BBPTF | |
| SCHEMBL26093063 | 0.67 | KAT2B (0.50) | KAT2BBPTF | |
| SCHEMBL26093572 | 0.67 | KAT2B (0.50) | KAT2BBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499639-B | Pyrimidone derivatives and their use in pharmacy | 四川大学华西医院 | 2022-03-04 | — | — | CN | disclosed |
| CN-111499639-A | Pyrimidone derivatives and their use in pharmacy | 四川大学华西医院 | 2020-08-07 | — | — | CN | disclosed |