SCHEMBL29412997

SCHEMBL29412997

CN1C[C@H](Nc2nc3cc[nH]c3c(=O)n2C)C[C@H](c2ccc3c(c2)OCCO3)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KAT2B Q92831 20/20 1.00
▸ BPTF Q12830 1/20 1.00
▸ KAT2A Q92830 1/20 1.00
▸ SETDB1 Q15047 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548080 1.00 KAT2B (1.00) KAT2BBPTFKAT2ASETDB1
SCHEMBL29413001 0.83 KAT2B (1.00) KAT2BBPTFKAT2ASETDB1
SCHEMBL26793287 0.75 KAT2B (0.59) KAT2BBPTFKAT2ASETDB1
SCHEMBL28438090 0.72 KAT2B (1.00) KAT2BBPTFKAT2ASETDB1
SCHEMBL28438091 0.72 KAT2B (1.00) KAT2BBPTFKAT2ASETDB1
SCHEMBL29413030 0.65 BPTF (0.46) KAT2BBPTFKAT2A
SCHEMBL28435004 0.65 BPTF (0.46) KAT2BBPTFKAT2A
SCHEMBL28431573 0.64 NPC1 (0.52) KAT2BBPTFKAT2A
SCHEMBL29413023 0.59 KAT2B (0.49) KAT2BSETDB1
SCHEMBL24870219 0.57 ACACB (0.45) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof FLAGSHIP PIONEERING, INC. (US) 2025-04-17 — — US disclosed
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-10-19 — — US disclosed
CN-115887668-A Application of composition or inhibitor for controlling KIF15 gene expression 广州希灵生物科技有限公司 2023-04-04 — — CN disclosed
CN-111499639-B Pyrimidone derivatives and their use in pharmacy 四川大学华西医院 2022-03-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, DDX21, SNRPE KAT2B 3350/4885BPTF 742/4885KAT2A 2590/4885
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof EFTUD2, DDX21, SNRPE KAT2B 3350/4885BPTF 742/4885KAT2A 2590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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