SCHEMBL31091734

SCHEMBL31091734

CN1C[C@H](Nc2nc3cc[nH]c3c(=O)n2C)C[C@H](c2ccc(C(=O)O)cc2)C1

nearest known ligand 0.81

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KAT2B Q92831 20/20 0.81
▸ SETDB1 Q15047 2/20 0.81
▸ BPTF Q12830 1/20 0.68
▸ KAT2A Q92830 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413001 0.89 KAT2B (1.00) KAT2BSETDB1BPTFKAT2A
SCHEMBL31091717 0.88 KAT2B (0.73) KAT2BSETDB1BPTFKAT2A
SCHEMBL29412997 0.81 KAT2B (1.00) KAT2BSETDB1BPTFKAT2A
SCHEMBL31091743 0.76 KAT2B (0.56) KAT2BSETDB1BPTFKAT2A
SCHEMBL28438090 0.74 KAT2B (1.00) KAT2BSETDB1BPTFKAT2A
SCHEMBL28438091 0.74 KAT2B (1.00) KAT2BSETDB1BPTFKAT2A
SCHEMBL30830502 0.70 KAT2B (0.67) KAT2BSETDB1BPTFKAT2A
SCHEMBL30830474 0.70 KAT2B (0.62) KAT2BSETDB1BPTFKAT2A
SCHEMBL30830559 0.69 KAT2B (0.79) KAT2BSETDB1BPTFKAT2A
SCHEMBL30830592 0.69 KAT2B (0.79) KAT2BBPTFKAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024220843-A1 TECHNOLOGIES TARGETING CELL STATES AURON THERAPEUTICS, INC. (US) 2024-10-24 — — WO disclosed
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