Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438115 | 0.82 | MEN1 (0.44) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL14208571 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL28434024 | 0.80 | CYP1A2 (0.38) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28442954 | 0.77 | LMNA (0.42) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL28058463 | 0.77 | CYP19A1 (0.56) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL28433235 | 0.75 | CNR2 (0.40) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL29756091 | 0.74 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL150572 | 0.74 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL28441417 | 0.74 | ALDH1A1 (0.43) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL28937725 | 0.73 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928121-B | High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound | 暨南大学 | 2020-05-12 | — | — | CN | disclosed |