SCHEMBL28438296

SCHEMBL28438296

CO[SiH](CCCCNCCN(C)C)OC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TDP1 Q9NUW8 1/20 0.39
PAOX Q6QHF9 1/20 0.37
PRMT3 O60678 1/20 0.33
CARM1 Q86X55 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
PRMT1 Q99873 1/20 0.33
PRMT8 Q9NR22 1/20 0.33
KDM1A O60341 1/20 0.33
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRM2 P08172 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17099814 0.92 TDP1 (0.48) CYP2C9CYP2C19TDP1PAOXKDM4E
SCHEMBL31133905 0.86 TDP1 (0.50) CYP2C9CYP2C19TDP1PAOXPRMT3
SCHEMBL28975742 0.85 TSHR (0.39) CYP2C9CYP2C19KDM1AALDH1A1SMN1; SMN2
SCHEMBL613797 0.79 ALDH1A1 (0.48) TDP1KDM4EALDH1A1SIGMAR1TSHR
SCHEMBL16100183 0.79 CYP2C19 (0.35) CYP2C19ALDH1A1TSHR
SCHEMBL614388 0.78 TSHR (0.44) CYP2C19PAOXKDM1AALDH1A1TSHR
SCHEMBL272669 0.78 TSHR (0.50) CYP2C19PAOXKDM1AALDH1A1SIGMAR1
SCHEMBL27989 0.78 CA12 (0.46) CYP2C9CYP2C19TDP1PAOXKDM4E
SCHEMBL1991712 0.77 ALDH1A1 (0.43) TDP1KDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL6444263 0.76 CA12 (0.44) CYP2C9CYP2C19TDP1PAOXKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115975279-A Municipal water supply pipeline plastic and preparation method thereof 江苏建宏管业科技有限公司 2023-04-18 CN claimed
CN-115895568-A Reactive single-component polyurethane hot melt adhesive and preparation method and application thereof 韦尔通科技股份有限公司 2023-04-04 CN claimed
CN-115785895-A Solvent-free sprayable condensed type silicone sealant and preparation method thereof 广州市白云化工实业有限公司 2023-03-14 CN claimed
CN-113774651-A Surface modification method for liquid crystal polymer material 上海普利特复合材料股份有限公司 2021-12-10 CN claimed
CN-109694498-B Montmorillonite carrier antibacterial agent for plastics and preparation method thereof 浙江通力新材料科技股份有限公司 2021-02-26 CN claimed
CN-109679188-B Antibacterial functional polymer master batch and packaging film 浙江凯利新材料股份有限公司 2021-02-09 CN claimed
CN-107501960-B Skin-feel hand feeling agent and preparation method thereof 岳阳凯门水性助剂有限公司 2020-06-26 CN claimed
CN-115975279-A Municipal water supply pipeline plastic and preparation method thereof 江苏建宏管业科技有限公司 2023-04-18 CN disclosed
CN-115895568-A Reactive single-component polyurethane hot melt adhesive and preparation method and application thereof 韦尔通科技股份有限公司 2023-04-04 CN disclosed
CN-115785895-A Solvent-free sprayable condensed type silicone sealant and preparation method thereof 广州市白云化工实业有限公司 2023-03-14 CN disclosed
CN-114736559-A high-L-value black ink for realizing integral black effect and preparation method thereof 惠州市百时达化工有限公司 2022-07-12 CN disclosed
CN-113774651-A Surface modification method for liquid crystal polymer material 上海普利特复合材料股份有限公司 2021-12-10 CN disclosed
CN-109694498-B Montmorillonite carrier antibacterial agent for plastics and preparation method thereof 浙江通力新材料科技股份有限公司 2021-02-26 CN disclosed
CN-109679188-B Antibacterial functional polymer master batch and packaging film 浙江凯利新材料股份有限公司 2021-02-09 CN disclosed
CN-107501960-B Skin-feel hand feeling agent and preparation method thereof 岳阳凯门水性助剂有限公司 2020-06-26 CN disclosed