Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13169086 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| SCHEMBL1132171 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| SCHEMBL14764073 | 0.98 | GPR84 (0.54) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| SCHEMBL27882168 | 0.98 | GPR84 (0.54) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| SCHEMBL1899646 | 0.98 | GPR84 (0.54) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| SCHEMBL25644937 | 0.94 | GPR84 (0.45) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| Acetic Acid SCHEMBL28649861 | 0.94 | GPR84 (0.45) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| Adipic Acid SCHEMBL27696355 | 0.94 | GPR84 (0.60) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| SCHEMBL7512899 | 0.93 | CAMK2A (0.50) | GPR84FFAR1FFAR4CAMK2ANPC1 | |
| Ethylene Glycol SCHEMBL11882187 | 0.93 | NPC1 (0.45) | GPR84FFAR1FFAR4CAMK2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634717-A | Plant fiber-based biodegradable tableware and preparation method thereof | 河北工程大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113234214-B | Copolyester and preparation method thereof | 中国科学院大连化学物理研究所 | 2022-02-15 | — | — | CN | disclosed |
| CN-113234214-A | Copolyester and preparation method thereof | 中国科学院大连化学物理研究所 | 2021-08-10 | — | — | CN | disclosed |
| CN-111500026-A | Environment-friendly plastic and preparation method thereof | 安徽华猫软包装有限公司 | 2020-08-07 | — | — | CN | disclosed |