SCHEMBL28438951

SCHEMBL28438951

COC(=O)c1ccc(NC(=O)c2ccccc2)cc1C(=O)OC

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.68
KMT2A Q03164 5/20 0.65
MAPT P10636 4/20 0.65
KDM4E B2RXH2 4/20 0.65
MEN1 O00255 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
LMNA P02545 1/20 0.65
PTPN1 P18031 1/20 0.61
PKM P14618 1/20 0.59
MAPK1 P28482 2/20 0.58
NPC1 O15118 5/20 0.58
NLRP3 Q96P20 1/20 0.57
KCNK9 Q9NPC2 4/20 0.57
KCNK3 O14649 3/20 0.57
HSD17B10 Q99714 1/20 0.57
HTT P42858 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6859800 0.88 MAPT (0.64) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL4238913 0.87 RAB9A (0.66) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL4241238 0.87 KMT2A (0.68) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL11170486 0.87 RAB9A (0.62) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL4246500 0.87 KDM4E (0.64) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL20522767 0.87 RAB9A (0.66) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL7050973 0.87 KCNK9 (0.67) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL4238475 0.83 MAPT (0.64) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL10153281 0.82 SMN1; SMN2 (0.59) RAB9AKMT2AMAPTKDM4EMEN1
SCHEMBL677770 0.81 RAB9A (1.00) RAB9AKMT2AMAPTMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109517152-B High-temperature self-crosslinking flame-retardant smoke-suppression anti-dripping copolyester based on benzamide structure and preparation method and application thereof 四川大学 2020-08-11 CN disclosed