SCHEMBL284390

SCHEMBL284390

CC(C)(CCC1CO1)OC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41
BCHE P06276 3/20 0.39
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
LMNA P02545 2/20 0.37
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
F2 P00734 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CES2 O00748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13864110 0.93 ELANE (0.35) CYP1A2CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL13864117 0.90 SLC7A5 (0.38) CYP1A2CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL13864119 0.87 TSHR (0.38) TSHRTDP1ALDH1A1BCHEMAPK1
SCHEMBL14473746 0.87 SERPINE1 (0.31) CYP1A2TSHRALDH1A1HIF1AMAPT
SCHEMBL263461 0.81 TDP1 (0.58) CYP1A2CYP2D6CYP2C19TSHRTDP1
SCHEMBL13864116 0.78 ALDH1A1 (0.36) CYP1A2TSHRTDP1ALDH1A1HIF1A
SCHEMBL1784040 0.78 CYP2D6 (0.51) CYP1A2CYP2D6CYP2C19TSHRTDP1
SCHEMBL27667888 0.78 CES1 (0.38) MEN1KMT2A
SCHEMBL13864107 0.77 ELANE (0.36) CYP1A2CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL16672886 0.77 CYP1A2 (0.48) CYP1A2CYP2D6CYP2C19TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3921399-A1 COMPRESSOR LUBRICANT COMPOSITION Total Marketing Services (FR) 2021-12-15 EP disclosed
WO-2020161051-A1 COMPRESSOR LUBRICANT COMPOSITION TOTAL MARKETING SERVICES (FR) 2020-08-13 WO disclosed
US-20190322958-A1 Lubricant Composition BASF SE (DE) 2019-10-24 US disclosed
US-10087345-B2 Pressure-sensitive adhesive composition, pressure-sensitive adhesive layer, pressure-sensitive adhesive tape, and double-coated pressure-sensitive adhesive tape NITTO DENKO CORPORATION (JP) 2018-10-02 US disclosed
US-10066186-B2 Lubricating oil compositions containing a halide seal compatibility additive and a second seal compatibility additive BASF SE (DE) 2018-09-04 US disclosed
WO-2018089416-A1 LUBRICANT COMPOSITION BASF SE (DE) 2018-05-17 WO disclosed
EP-2161323-B1 LUBRICANT COMPOSITION FOR REFRIGERATOR AND COMPRESSOR USING THE SAME IDEMITSU KOSAN CO (JP) 2017-08-23 EP disclosed
US-9677023-B2 Lubricating oil compositions containing seal compatibility additives and sterically hindered amines BASF SE (DE) 2017-06-13 US disclosed
EP-3129454-A1 LUBRICATING OIL COMPOSITIONS CONTAINING SEAL COMPATIBILITY ADDITIVES AND STERICALLY HINDERED AMINES BASF SE (DE) 2017-02-15 EP disclosed
US-20170029737-A1 LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS BASF SE (DE) 2017-02-02 US disclosed
US-20020115577-A1 Refrigerating machine oil, and fluid composition for refrigerating machine NIPPON MITSUBISHI OIL CORPORATION (JP) 2002-08-22 US disclosed
US-20020098993-A1 Refrigerating machine oil for carbon dioxide refrigerant and fluid composition for refrigerating machine NIPPON MITSUBISHI OIL CORPORATION 2002-07-25 US disclosed
EP-1211302-A1 Base oil for carbon dioxide refrigerant and refrigerating machine oil composition Nippon Mitsubishi Oil Corporation (JP) 2002-06-05 EP disclosed
EP-1205534-A1 REFRIGERATING OIL COMPOSITION Nippon Mitsubishi Oil Corporation (JP) 2002-05-15 EP disclosed
EP-1201733-A1 REFRIGERATING MACHINE OIL COMPOSITION Nippon Mitsubishi Oil Corporation (JP) 2002-05-02 EP disclosed
EP-1199348-A1 Refrigerating machine oil, and fluid composition for refrigerating machine using CO2 as refrigerant Nippon Mitsubishi Oil Corporation (JP) 2002-04-24 EP disclosed
US-6355186-B1 Refrigerating machine oil composition NIPPON MITSUBISHI OIL CORPORATION (JP) 2002-03-12 US disclosed
EP-1184446-A1 REFRIGERATING MACHINE OIL COMPOSITION Nippon Mitsubishi Oil Corporation (JP) 2002-03-06 EP disclosed
US-6231782-B1 HYDROCARBON OIL, ALICYCLIC POLYCARBOXYLIC ACID ESTER COMPOUND HAVING AN ALICYCLIC RING AND AT LEAST TWO ESTER GROUPS, REFRIGERANT SELECTED FROM HYDROFLUOROCARBON REFRIGERANTS, FLUORINE-CONTAINING, FLUORINE-FREE ETHERS NIPPON MITSUBISHI OIL CORP. (JP) 2001-05-15 US disclosed
US-6228282-B1 A REFRIGERATING MACHINE OIL CONTAINING A SPECIFIC POLYCARBOXYLIC ACID ESTER COMPOUND AND A SPECIFIC EPOXY COMPOUND, REFRIGERANT SELECTED FROM HYDROFLUOROCARBON, FLUOROETHERS, FLUORINE-FREE ETHER, AND NATURAL NIPPON MITSUBISHI OIL CORP. (JP) 2001-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115577-A1 Refrigerating machine oil, and fluid composition for refrigerating machine ERN1, MED1, GCN1 CYP1A2 1037/4885CYP2D6 3689/4885CYP2C19 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.