Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444878 | 0.93 | KDM4E (0.51) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL2446597 | 0.86 | MEN1 (0.51) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL2446258 | 0.83 | KDM4E (0.50) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL28434980 | 0.83 | CYP1A2 (0.44) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL2444783 | 0.81 | MAPT (0.51) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL28431144 | 0.81 | KDM4E (0.32) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL2446243 | 0.79 | KDM4E (0.44) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL2443998 | 0.79 | KDM4E (0.43) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL2441656 | 0.78 | KDM4E (0.44) | SMN1; SMN2MEN1LMNAKMT2AKDM4E | |
| SCHEMBL2445421 | 0.78 | ESR1 (0.45) | SMN1; SMN2MEN1LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997580-B | Polyether imide containing anthrone and trifluoromethyl structures and preparation method thereof | 江西师范大学 | 2020-07-28 | — | — | CN | disclosed |